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Comment
. 2010 Nov 12;143(4):503-5.
doi: 10.1016/j.cell.2010.10.036.

Shining a light on germinal center B cells

Jason G Cyster  1
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Shining a light on germinal center B cells

Jason G Cyster. Cell. .
Free article

Abstract

The mechanisms of B cell selection in lymphoid tissues are poorly understood. In this issue, Victora et al. (2010) use imaging of photoactivatable green fluorescent protein to define the movements of B cells in germinal centers and provide evidence that antibody affinity maturation is driven by competition for T cell help.

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