Case Reports
doi: 10.1016/j.ajem.2010.09.039.
Epub 2010 Nov 13.
Ciprofloxacin-induced torsade de pointes
Affiliations
- PMID: 21075583
- DOI: 10.1016/j.ajem.2010.09.039
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Case Reports
Ciprofloxacin-induced torsade de pointes
Am J Emerg Med.
2012 Jan.
Abstract
A 65-year-old man with recently diagnosed urinary tract infection treated with ciprofloxacin (Cipro) presented to our institution with recurrent seizure-like activity. His rhythm revealed torsade de pointes, which required defibrillation. Subsequent electrocardiogram revealed severely prolonged QT interval, which near-completely resolved 7 days later off Cipro. This case highlights a rare but potentially fatal side effect of quinolone antibiotics, especially in combination with other QT-prolonging medications. Review of the literature with regard to prevalence, mechanism, and assessment and treatment of this potentially fatal incidence is provided.
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