A prospective assessment of the role of bronchoscopy and bronchoalveolar lavage in evaluation of children with pulmonary tuberculosis
- PMID: 21075785
- DOI: 10.1093/tropej/fmq105
A prospective assessment of the role of bronchoscopy and bronchoalveolar lavage in evaluation of children with pulmonary tuberculosis
Abstract
Objective: To assess the diagnostic yield of fibreoptic bronchoscopy and bronchoalveolar lavage (BAL) compared to gastric aspiration (GA) in children with probable pulmonary tuberculosis (TB).
Methods: Children with probable pulmonary TB were subjected to bronchoscopy, BAL and gastric aspiration. The samples were examined for acid fast bacilli (AFB) on smear.
Results: A total of 52 children underwent bronchoscopy with BAL and GA. AFB on smear was identified in 19 (36.5%); BAL was positive in 16 (30.8%) and GA was positive in 11 (21.15%). GA alone was positive in 3 (5.67%) while BAL alone was positive in 8 (15.38%). Bronchoscopy detected airways' abnormality in 29 (56%) of patients. One GA and BAL detected AFB in majority of patients.
Conclusion: The diagnostic yield for AFB from BAL was better than that from GA in children with probable pulmonary TB. Combining one GA and bronchoscopy may improve AFB yield in children with pulmonary TB.
Similar articles
-
Role of gastric lavage and broncho-alveolar lavage in the bacteriological diagnosis of childhood pulmonary tuberculosis.Indian Pediatr. 2000 Sep;37(9):947-51. Indian Pediatr. 2000. PMID: 10992330
-
Value of bronchoalveolar lavage and gastric lavage in the diagnosis of pulmonary tuberculosis in children.Tuber Lung Dis. 1995 Aug;76(4):295-9. doi: 10.1016/s0962-8479(05)80027-9. Tuber Lung Dis. 1995. PMID: 7579310 Clinical Trial.
-
The value of nasopharyngeal aspirate, gastric aspirate and bronchoalveolar lavage fluid in the diagnosis of childhood tuberculosis.Turk J Pediatr. 2018;60(1):10-13. doi: 10.24953/turkjped.2018.01.002. Turk J Pediatr. 2018. PMID: 30102474
-
The role of bronchoscopy in the diagnosis and management of pediatric pulmonary tuberculosis.Expert Rev Respir Med. 2014 Feb;8(1):101-9. doi: 10.1586/17476348.2013.863712. Epub 2013 Dec 30. Expert Rev Respir Med. 2014. PMID: 24378192 Review.
-
The role of routine culture for tuberculosis during bronchoscopy in a nonendemic area: analysis of 300 cases and review of the literature.Am J Infect Control. 2005 Dec;33(10):602-5. doi: 10.1016/j.ajic.2005.05.010. Am J Infect Control. 2005. PMID: 16330309 Review.
Cited by
-
The Value of Bronchoalveolar Lavage in the Diagnosis of Sputum Smear-NegativePulmonary Tuberculosis.Iran J Pathol. 2015 Winter;10(1):35-40. Iran J Pathol. 2015. PMID: 26516323 Free PMC article.
-
Can Intensified Tuberculosis Case Finding Efforts at Nutrition Rehabilitation Centers Lead to Pediatric Case Detection in Bihar, India?J Tuberc Res. 2016 Mar 30;4(1):46-54. doi: 10.4236/jtr.2016.41006. J Tuberc Res. 2016. PMID: 27066518 Free PMC article.
-
The Significance of Bronchoalveolar Lavage Fluid Cytology in Diagnosing Lung Infiltrates in Children.Med Arch. 2016 Feb;70(1):27-30. doi: 10.5455/medarh.2016.70.27-30. Epub 2016 Jan 31. Med Arch. 2016. PMID: 26980927 Free PMC article.
-
Bronchoalveolar Lavage Xpert MTB/RIF Assay for Rapid Diagnosis of Smear Negative Pulmonary Tuberculosis in Children.Indian J Pediatr. 2024 Dec;91(12):1289. doi: 10.1007/s12098-024-05231-w. Epub 2024 Aug 15. Indian J Pediatr. 2024. PMID: 39143394 No abstract available.
-
Diagnostic Yield of Xpert MTB/RIF Assay Using Bronchoalveolar Lavage Fluid in Detecting Mycobacterium tuberculosis among the Sputum-Scarce Suspected Pulmonary TB Patients.Diagnostics (Basel). 2022 Jul 10;12(7):1676. doi: 10.3390/diagnostics12071676. Diagnostics (Basel). 2022. PMID: 35885580 Free PMC article.
Publication types
MeSH terms
LinkOut - more resources
Full Text Sources
