Conformational stability of globular proteins
- PMID: 2107612
- DOI: 10.1016/0968-0004(90)90124-t
Conformational stability of globular proteins
Abstract
The conformational stability of ribonuclease T1 has been measured as a function of the variables of most interest to biochemists: temperature, pH, salt concentration, disulfide-bond content and amino acid sequence. The results provide insight into the forces that stabilize globular proteins.
Similar articles
-
Conformational stability and activity of ribonuclease T1 with zero, one, and two intact disulfide bonds.J Biol Chem. 1988 Aug 25;263(24):11820-5. J Biol Chem. 1988. PMID: 2457027
-
pH dependence of the urea and guanidine hydrochloride denaturation of ribonuclease A and ribonuclease T1.Biochemistry. 1990 Mar 13;29(10):2564-72. doi: 10.1021/bi00462a019. Biochemistry. 1990. PMID: 2110472
-
Contribution of hydrogen bonding to the conformational stability of ribonuclease T1.Biochemistry. 1992 Jan 28;31(3):725-32. doi: 10.1021/bi00118a013. Biochemistry. 1992. PMID: 1731929
-
Crystallographic study of mechanism of ribonuclease T1-catalysed specific RNA hydrolysis.J Biomol Struct Dyn. 1983 Oct;1(2):523-38. doi: 10.1080/07391102.1983.10507459. J Biomol Struct Dyn. 1983. PMID: 6086061 Review.
-
Forces contributing to the conformational stability of proteins.FASEB J. 1996 Jan;10(1):75-83. doi: 10.1096/fasebj.10.1.8566551. FASEB J. 1996. PMID: 8566551 Review.
Cited by
-
pH dependence thermal stability of a chymotrypsin inhibitor from Schizolobium parahyba seeds.Biophys J. 2005 May;88(5):3509-17. doi: 10.1529/biophysj.104.045682. Epub 2005 Mar 11. Biophys J. 2005. PMID: 15764660 Free PMC article.
-
Salt-bridge energetics in halophilic proteins.PLoS One. 2014 Apr 17;9(4):e93862. doi: 10.1371/journal.pone.0093862. eCollection 2014. PLoS One. 2014. PMID: 24743799 Free PMC article.
-
Probing the determinants of protein stability: comparison of class A beta-lactamases.Biochem J. 1995 Jun 15;308 ( Pt 3)(Pt 3):859-64. doi: 10.1042/bj3080859. Biochem J. 1995. PMID: 8948443 Free PMC article.
-
Coordinate and non-coordinate expression of the stress 70 family and other molecular chaperones at high and low temperature in spinach and tomato.Plant Mol Biol. 1999 Jan;39(1):21-34. doi: 10.1023/a:1006100532501. Plant Mol Biol. 1999. PMID: 10080706
-
Structural features responsible for the biological stability of Histoplasma's virulence factor CBP.Biochemistry. 2008 Apr 15;47(15):4427-38. doi: 10.1021/bi701495v. Epub 2008 Mar 25. Biochemistry. 2008. PMID: 18361504 Free PMC article.
Publication types
MeSH terms
Substances
Grants and funding
LinkOut - more resources
Full Text Sources
Other Literature Sources