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. 2010 Dec;6(12):868-70.
doi: 10.1038/nchembio.469.

Grand challenge commentary: Beyond discovery: probes that see, grab and poke

Affiliations

Grand challenge commentary: Beyond discovery: probes that see, grab and poke

Joshua A Kritzer. Nat Chem Biol. 2010 Dec.

Abstract

Chemical biology is now able to discover molecules that manipulate virtually any biological target or process. It remains a grand challenge to leverage these molecules into useful probes that can be used to address unsolved problems in biology.

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References

    1. Mol Ther. 2006 Apr;13(4):644-70 - PubMed
    1. Nat Chem Biol. 2007 Aug;3(8):447-50 - PubMed
    1. Nat Chem Biol. 2009 Sep;5(9):616-24 - PubMed
    1. J Biol Chem. 2010 Apr 9;285(15):11033-8 - PubMed
    1. Curr Opin Biotechnol. 2002 Oct;13(5):459-67 - PubMed

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