Pharmacogenetics: Clinical response to antiplatelet therapy--how much does genotype count?
- PMID: 21080597
- DOI: 10.1038/nrcardio.2010.146
Pharmacogenetics: Clinical response to antiplatelet therapy--how much does genotype count?
Comment on
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Genetic variants in ABCB1 and CYP2C19 and cardiovascular outcomes after treatment with clopidogrel and prasugrel in the TRITON-TIMI 38 trial: a pharmacogenetic analysis.Lancet. 2010 Oct 16;376(9749):1312-9. doi: 10.1016/S0140-6736(10)61273-1. Lancet. 2010. PMID: 20801494 Free PMC article.
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Effect of CYP2C19 and ABCB1 single nucleotide polymorphisms on outcomes of treatment with ticagrelor versus clopidogrel for acute coronary syndromes: a genetic substudy of the PLATO trial.Lancet. 2010 Oct 16;376(9749):1320-8. doi: 10.1016/S0140-6736(10)61274-3. Lancet. 2010. PMID: 20801498
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Effects of CYP2C19 genotype on outcomes of clopidogrel treatment.N Engl J Med. 2010 Oct 28;363(18):1704-14. doi: 10.1056/NEJMoa1008410. Epub 2010 Aug 29. N Engl J Med. 2010. PMID: 20979470 Clinical Trial.
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