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. 2011 Feb;28(2):151-6.
doi: 10.1007/s10815-010-9497-1. Epub 2010 Nov 17.

Long Y chromosome is not a fetal loss risk

Hongchuan Nie  1 , Guangxiu Lu
Affiliations

Long Y chromosome is not a fetal loss risk

Hongchuan Nie et al. J Assist Reprod Genet. 2011 Feb.

Abstract

Purpose: To assess the long Y chromosome genetic effect on human pregnancy outcomes.

Methods: We studied all records of pregnancies by human sperm donors after artificial insemination or in vitro fertilization at the Reproductive and Genetic Hospital of Citic-Xiangya. Fetal losses were compared from two groups of sperm donors: the observation group (with long Y chromosome) and the control group (without long Y chromosome).

Results: 2885 pregnancies were achieved with donor sperm by artificial insemination and 1746 by in vitro fertilization. The rates of fetal loss, congenital malformation and donor fecundity in the observation group after both assisted reproductive technique were the same as for the control group.

Conclusions: A long Y chromosome may therefore be considered as a normal variant.

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