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. 2010 Oct;70(4):597-603.
doi: 10.1111/j.1365-2125.2009.03591.x.

What is the right dose for children?

Massimo Cella  1 , Catherijne Knibbe, Meindert Danhof, Oscar Della Pasqua
Affiliations

What is the right dose for children?

Massimo Cella et al. Br J Clin Pharmacol. 2010 Oct.
No abstract available

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Figures

Figure 1
Figure 1
Ratio of exposures to chloramphenicol between children and adults. Solid line: original dose (50 mg kg−1 day−1). Dashed lined: dose adjustment to avoid grey baby syndrome (25 mg kg−1 day−1 for babies up to 1 month). Empirical scaling of the paediatric dose based on body weight has led to overexposure to chloramphenicol
See this image and copyright information in PMC

References

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    1. European Parliament and Council of the European Union. Regulation (EC) No. 1901/2006 on medicinal products for paediatric use. 12 December 2006.
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