Human listeriosis in Britain, 1967-85, a summary of 722 cases. 1. Listeriosis during pregnancy and in the newborn

Abstract

Clinical information was collected on 722 cases of Listeria monocytogenes infections in humans occurring in Britain between 1967 and 1985: 248 cases (34%) were associated with pregnancy (maternal, foetal, and neonatal), and comprised 9 cases (4%) of maternal bacteraemia without infection of the foetus; 42 cases (19%) of intra-uterine deaths; 118 cases (54%) of neonatal infection diagnosed within 2 days post-partum; and 50 cases (23%) of neonatal infection diagnosed as ill after 2 days post-partum. An overall mortality of 50% was recorded. The cases unassociated with pregnancy are described elsewhere (see accompanying paper).