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Review
. 2011 Mar;33(3):469-76.
doi: 10.1007/s10529-010-0473-8. Epub 2010 Nov 19.

Aspergillus as a multi-purpose cell factory: current status and perspectives

Vera Meyer  1 , Bo Wu, Arthur F J Ram
Affiliations
Review

Aspergillus as a multi-purpose cell factory: current status and perspectives

Vera Meyer et al. Biotechnol Lett. 2011 Mar.

Abstract

Aspergilli have a long history in biotechnology as expression platforms for the production of food ingredients, pharmaceuticals and enzymes. The achievements made during the last years, however, have the potential to revolutionize Aspergillus biotechnology and to assure Aspergillus a dominant place among microbial cell factories. This mini-review will highlight most recent breakthroughs in fundamental and applied Aspergillus research with a focus on new molecular tools, techniques and products. New trends and concepts related to Aspergillus genomics and systems biology will be discussed as well as the challenges that have to be met to integrate omics data with metabolic engineering attempts.

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Figures

Fig. 1
Fig. 1
Number of Aspergillus omics articles published over the last years in Pubmed (by October 2010)
See this image and copyright information in PMC

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Publication types

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