Trapped versus soluble chemokines: functions in leukocyte adhesion and motility
- PMID: 21094462
- DOI: 10.1016/j.immuni.2010.11.012
Trapped versus soluble chemokines: functions in leukocyte adhesion and motility
Abstract
In this issue of Immunity, Bao et al. (2010) provide in vivo evidence that heparan sulfate glycosaminoglycans (GAGs) are indispensable for immobilization and function of major chemokines required for leukocyte adhesion to and crossing through blood and lymphatic vessels.
Copyright © 2010 Elsevier Inc. All rights reserved.
Comment on
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Endothelial heparan sulfate controls chemokine presentation in recruitment of lymphocytes and dendritic cells to lymph nodes.Immunity. 2010 Nov 24;33(5):817-29. doi: 10.1016/j.immuni.2010.10.018. Immunity. 2010. PMID: 21093315 Free PMC article.
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