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. 2011 Jan;15(1):e54-7.
doi: 10.1016/j.ijid.2010.09.011. Epub 2010 Nov 20.

The obesity paradox in community-acquired bacterial pneumonia

Vicente F Corrales-Medina  1 , Josemon Valayam, Jose A Serpa, Adriana M Rueda, Daniel M Musher
Affiliations
Free article

The obesity paradox in community-acquired bacterial pneumonia

Vicente F Corrales-Medina et al. Int J Infect Dis. 2011 Jan.
Free article

Abstract

Background: The impact of obesity on the outcome of pneumonia is uncertain.

Methods: We retrospectively identified 266 hospitalized patients with proven pneumococcal or Haemophilus community-acquired pneumonia who had at least one body mass index (BMI, kg/m²) value documented in the 3 months before admission. Patients were classified as underweight (BMI <18.5), normal weight (BMI 18.5 to <25), overweight (BMI 25 to <30), or obese (BMI ≥30). The association of absolute BMI values and BMI categories with the mortality at 30 days after admission for pneumonia was investigated.

Results: Increasing BMI values were associated with reduced 30-day mortality, even after adjustment for significant covariates (odds ratio 0.88, confidence interval 0.81-0.96; p<0.01). There was a significant trend towards lower mortality in the overweight and obese (non-parametric trend, p=0.02).

Conclusions: Our data suggest that obesity may exert a protective effect against 30-day mortality from community-acquired bacterial pneumonia.

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