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Review
. 2010 Dec;39(4):839-52.
doi: 10.1016/j.ecl.2010.08.006.

The role of angiogenesis in neuroendocrine tumors

John Lyons 3rd  1 , Catherine T Anthony, Eugene A Woltering
Affiliations
Review

The role of angiogenesis in neuroendocrine tumors

John Lyons 3rd et al. Endocrinol Metab Clin North Am. 2010 Dec.

Abstract

The first studies to assess in vitro angiogenesis in neuroendocrine tumors used animal-based assays to study the antiangiogenic properties of somatostatin analogs. Current technologies enable investigators to directly appraise the in vitro angiogenic response of an individual's neuroendocrine tumor with and without potential antiangiogenic reagents. This article describes the evolution of methods to assess in vitro angiogenesis in neuroendocrine tumors and describes some of the clinical data.

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