A pause to splice
- PMID: 21095579
- DOI: 10.1016/j.molcel.2010.11.019
A pause to splice
Abstract
Maturation of mRNA termini occurs during transcription and can be aided by pausing of RNA polymerase II (RNAPII). In this issue of Molecular Cell, two groups now demonstrate that RNAPII pausing may also assist cotranscriptional splicing in S. cerevisiae.
Copyright © 2010 Elsevier Inc. All rights reserved.
Comment on
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Global analysis of nascent RNA reveals transcriptional pausing in terminal exons.Mol Cell. 2010 Nov 24;40(4):571-81. doi: 10.1016/j.molcel.2010.11.004. Mol Cell. 2010. PMID: 21095587
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Splicing-dependent RNA polymerase pausing in yeast.Mol Cell. 2010 Nov 24;40(4):582-93. doi: 10.1016/j.molcel.2010.11.005. Mol Cell. 2010. PMID: 21095588 Free PMC article.
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