Lactose intolerance
- PMID: 2109963
- DOI: 10.1146/annurev.me.41.020190.001041
Lactose intolerance
Abstract
Lactose intolerance is a prevalent clinical problem. Low lactase levels result either from intestinal injury, or as in the majority of the world's adult population, from alterations in the genetic expression of lactase-phlorizin hydrolase. Progress is being made in the basic understanding of the molecular and cellular biology of this enzyme and of the scientific basis of clinical syndromes involving low lactase activity.
Similar articles
-
Lactose intolerance and the genetic regulation of intestinal lactase-phlorizin hydrolase.FASEB J. 1991 Oct;5(13):2824-32. doi: 10.1096/fasebj.5.13.1916106. FASEB J. 1991. PMID: 1916106 Review.
-
Clinical aspects of lactose intolerance in children and adults.Scand J Gastroenterol Suppl. 1991;188:73-80. doi: 10.3109/00365529109111233. Scand J Gastroenterol Suppl. 1991. PMID: 1775944 Review.
-
The Diverse Forms of Lactose Intolerance and the Putative Linkage to Several Cancers.Nutrients. 2015 Aug 28;7(9):7209-30. doi: 10.3390/nu7095332. Nutrients. 2015. PMID: 26343715 Free PMC article. Review.
-
Human adult-onset lactase decline: an update.Nutr Rev. 1998 Jan;56(1 Pt 1):1-8. doi: 10.1111/j.1753-4887.1998.tb01652.x. Nutr Rev. 1998. PMID: 9481112 Review.
-
Genetics of Lactose Intolerance: An Updated Review and Online Interactive World Maps of Phenotype and Genotype Frequencies.Nutrients. 2020 Sep 3;12(9):2689. doi: 10.3390/nu12092689. Nutrients. 2020. PMID: 32899182 Free PMC article. Review.
Cited by
-
Structural hierarchy of regulatory elements in the folding and transport of an intestinal multidomain protein.J Biol Chem. 2010 Feb 5;285(6):4143-4152. doi: 10.1074/jbc.M109.060780. Epub 2009 Dec 2. J Biol Chem. 2010. PMID: 19955176 Free PMC article.
-
Lactase-phlorizin hydrolase and aminopeptidase N are differentially regulated in the small intestine of the pig.Biochem J. 1993 Oct 1;295 ( Pt 1)(Pt 1):177-82. doi: 10.1042/bj2950177. Biochem J. 1993. PMID: 8105780 Free PMC article.
-
Ontogeny, growth and development of the small intestine: Understanding pediatric gastroenterology.World J Gastroenterol. 2010 Feb 21;16(7):787-99. doi: 10.3748/wjg.v16.i7.787. World J Gastroenterol. 2010. PMID: 20143457 Free PMC article. Review.
-
Effects of exogenous lactase administration on hydrogen breath excretion and intestinal symptoms in patients presenting lactose malabsorption and intolerance.Biomed Res Int. 2014;2014:680196. doi: 10.1155/2014/680196. Epub 2014 May 25. Biomed Res Int. 2014. PMID: 24967391 Free PMC article. Clinical Trial.
-
Consensus report of the National Medical Association. The role of dairy and dairy nutrients in the diet of African Americans.J Natl Med Assoc. 2004 Dec;96(12 Suppl):5S-31S. J Natl Med Assoc. 2004. PMID: 15624290 Free PMC article. Review. No abstract available.
Publication types
MeSH terms
Substances
LinkOut - more resources
Full Text Sources
Other Literature Sources
Medical