Statistical interaction in human genetics: how should we model it if we are looking for biological interaction?
- PMID: 21102529
- PMCID: PMC5189671
- DOI: 10.1038/nrg2579-c2
Statistical interaction in human genetics: how should we model it if we are looking for biological interaction?
Comment on
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Detecting gene-gene interactions that underlie human diseases.Nat Rev Genet. 2009 Jun;10(6):392-404. doi: 10.1038/nrg2579. Nat Rev Genet. 2009. PMID: 19434077 Free PMC article. Review.
References
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- Fisher R. The correlation between relatives on the supposition of Mendelian inheritance. Trans. R. Soc. Edinb. 1918;52:399–433.
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- Siemiatycki J, Thomas DC. Biological models and statistical interactions: an example from multistage carcinogenesis. Int. J. Epidemiol. 1981;10:383–387. - PubMed
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