doi: 10.1364/AO.35.003441.
Sources of contrast in confocal reflectance imaging
- PMID: 21102733
- DOI: 10.1364/AO.35.003441
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Sources of contrast in confocal reflectance imaging
Appl Opt.
.
Abstract
The relationship between optical properties and image contrast in confocal imaging is investigated. A Monte Carlo simulation has been developed to analyze the effects of changes in scattering, index of refraction, and absorption in a three-layer medium. Contrast was calculated from the computed signal-to-background ratios for changes in tissue optical properties. Results show that the largest source of contrast is changes in refractive index.
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