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. 2008 Jul;1(2):38-41.

Calciphylaxis: a review

Avani Bhambri  1 , James Q Del Rosso
Affiliations

Calciphylaxis: a review

Avani Bhambri et al. J Clin Aesthet Dermatol. 2008 Jul.

Abstract

Calciphylaxis is a condition involving vascular calcification and cutaneous necrosis. The mortality rate is high, with more than 50 percent of patients dying within one year of diagnosis. The exact pathogenesis of calciphylaxis is unclear. Lower extremities are most commonly involved. Intravascular calcium deposition in the media of the dermal and subcutaneous arterioles is the diagnostic histopathologic feature seen. Treatment options include wound care, surgical debridement, sodium thiosulfate, bisphosphonates, and hyperbaric oxygen.

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Figures

Figure 1
Figure 1
Indurated plaques on the abdomen accompanied by scattered flaccid bullae and erosions
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