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Review
. 1990 Feb;11(2):55-9.
doi: 10.1016/0167-5699(90)90019-6.

Dissection of an inflammatory process induced by CD8+ T cells

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Review

Dissection of an inflammatory process induced by CD8+ T cells

P C Doherty et al. Immunol Today. 1990 Feb.

Abstract

A massive delayed type hypersensitivity (DTH) reaction occurs in the cerebrospinal fluid (CSF) of mice with lymphocytic choriomeningitis (LCM). In this article, Peter Doherty and colleagues analyze this reaction together with the population dynamics of the regional lymph node to give a comprehensive picture of the events underlying this CD8+ T-cell-mediated immunopathological disease. Their findings are of general relevance to the understanding of inflammation.

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