Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Review
. 2010 Nov 28;16(44):5598-602.
doi: 10.3748/wjg.v16.i44.5598.

Left-sided appendicitis: review of 95 published cases and a case report

Affiliations
Review

Left-sided appendicitis: review of 95 published cases and a case report

Sami Akbulut et al. World J Gastroenterol. .

Abstract

Aim: To give an overview of the literature on left-sided acute appendicitis (LSAA) associated with situs inversus totalis (SIT) and midgut malrotation (MM).

Methods: We present a new case of LSAA with SIT and a literature review of studies published in the English language on LSAA, accessed via PubMed and Google Scholar databases.

Results: Ninety-five published cases of LSAA were evaluated and a 25-year-old female, who presented to our clinic with left lower abdominal pain caused by LSAA, is reported. In the reviewed literature, fifty-seven patients were male and 38 were female with an age range of 8 to 82 years and a median age of 29.1 ± 15.9 years. Sixty-six patients had SIT, 23 had MM, three had cecal malrotation, and two had a previously unnoted congenital abnormality. Fifty-nine patients had presented to the hospital with left lower, 14 with right lower and seven with bilateral lower quadrant pain, and seven subjects complained of left upper quadrant pain. The diagnosis was established preoperatively in 49 patients, intraoperatively in 19, and during the postoperative period in five; 14 patients were aware of having this anomaly. The data of eight patients were not unavailable. Eleven patients underwent laparoscopic appendectomy, which was combined with cholecystectomy in two cases. Histopathological examination of the appendix specimens revealed adenocarcinoma in only two of 95 patients.

Conclusion: The diagnosis of left lower quadrant pain is based on well-established clinical symptoms, physical examination and physician's experience.

PubMed Disclaimer

Figures

Figure 1
Figure 1
Chest X-ray showing dextrocardia.
Figure 2
Figure 2
Intraoperative photograph showing an appendix together with cecum in the left lower quadrant.
Figure 3
Figure 3
Coronal contrast-enhanced multidetector computed tomography of the thorax, abdomen and pelvis. Computed tomography showed situs inversus totalis including dextrocardia, right-sided gastric bubble and reversed spleen and liver (postoperative view).

References

    1. Akbulut S, Caliskan A, Ekin A, Yagmur Y. Left-sided acute appendicitis with situs inversus totalis: review of 63 published cases and report of two cases. J Gastrointest Surg. 2010;14:1422–1428. - PubMed
    1. Hou SK, Chern CH, How CK, Kao WF, Chen JD, Wang LM, Huang CI. Diagnosis of appendicitis with left lower quadrant pain. J Chin Med Assoc. 2005;68:599–603. - PubMed
    1. Franklin ME Jr, Almeida JA, Pérez ER, Michaelson RLP, Majarrez A. Cholecystectomy and appendectomy by laparoscopy in a patient with situs inversus totalis: A case report and review of the literature. Asoc Mex Cir Endoscopica. 2001;2:150–153.
    1. Lee MR, Kim JH, Hwang Y, Kim YK. A left-sided periappendiceal abscess in an adult with intestinal malrotation. World J Gastroenterol. 2006;12:5399–5400. - PMC - PubMed
    1. van Steensel CJ, Wereldsma JC. Acute appendicitis in complete situs inversus. Neth J Surg. 1985;37:117–118. - PubMed

MeSH terms