Review
doi: 10.1016/j.intimp.2010.11.018.
Epub 2010 Nov 23.
Immunosuppressive and anti-inflammatory activities of sinomenine
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- PMID: 21109035
- DOI: 10.1016/j.intimp.2010.11.018
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Review
Immunosuppressive and anti-inflammatory activities of sinomenine
Int Immunopharmacol.
2011 Mar.
Abstract
Sinomenine (SN), a pure compound extracted from the Sinomenium acutum plant, has been found to inhibit T- and B-lymphocyte activation, proliferation and function and to interfere with the differentiation, recruitment and function of several other cell types, such as dendritic cells (DC). SN has demonstrated its potential anti-inflammatory role for treating immune-related disorders in experimental animal models and in some clinical applications. This review will summarize its potential effects, mechanisms and applications.
Crown Copyright © 2010. Published by Elsevier B.V. All rights reserved.
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