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Comparative Study
. 1978 Jul 12;56(3-4):197-201.
doi: 10.1007/BF00495980.

Immunoenzymehistochemical demonstration of the binding of low density lipoproteins to cultured human fibroblasts

Comparative Study

Immunoenzymehistochemical demonstration of the binding of low density lipoproteins to cultured human fibroblasts

B J Vermeer et al. Histochemistry. .

Abstract

Using as indirect cytochemical immunoperoxidase technique, we were able to demonstrate the binding of low density lipoprotein to cultured human fibroblasts. With this technique, fibroblasts from a patient suffering from homozygous hyperlipoproteinaemia type IIa did not show this binding. The method described here allows study of the localization of unmodified low density lipoproteins binding to cultured fibroblasts.

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