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. 2010 Nov 24;143(5):677-81.
doi: 10.1016/j.cell.2010.10.026.

What determines the specificity and outcomes of ubiquitin signaling?

Fumiyo Ikeda  1 , Nicola Crosetto, Ivan Dikic
Affiliations
Free article

What determines the specificity and outcomes of ubiquitin signaling?

Fumiyo Ikeda et al. Cell. .
Free article

Abstract

Ubiquitin signals and ubiquitin-binding domains are implicated in almost every cellular process, but how is their functionality achieved in cells? We assess recent advances in monitoring the dynamics and specificity of ubiquitin networks in vivo and discuss challenges ahead.

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