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. 2011 Jan;92(1):2-3.
doi: 10.1016/j.exer.2010.11.009. Epub 2010 Nov 24.

Focus on molecules: galectin-3

Pablo Argüeso  1 , Noorjahan Panjwani
Affiliations

Focus on molecules: galectin-3

Pablo Argüeso et al. Exp Eye Res. 2011 Jan.
No abstract available

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Figures

Figure 1
Figure 1
A. Genomic organization and protein structure of galectin-3. The Roman numerals indicate the position of the exons. The size of introns and polypeptide coding sequences are given in kb and bp, respectively. Galectin-3 consists of an N-terminal domain, 100-150 amino acids according to species of origin, and a C-terminal domain of about 135 amino acids, containing one carbohydrate recognition domain (CRD). B. Galectin-3 assembles in pentamer formation in the presence of multivalent ligands, in a process mediated through the N-terminal domain. At the cell surface, galectin-3 participates in cell-cell and cell-extracellular matrix (ECM) interactions, receptor clustering and signal transduction, and in the formation of glycoprotein-galectin lattices.
See this image and copyright information in PMC

References

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