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Comment
. 2010 Nov 30:6:443.
doi: 10.1038/msb.2010.100.

A global protein-lipid interactome map

Marc Brehme  1 , Marc Vidal
Affiliations
Comment

A global protein-lipid interactome map

Marc Brehme et al. Mol Syst Biol. .
No abstract available

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Conflict of interest statement

The authors declare conflicting interests. In addition to their affiliation with the Center for Cancer Systems Biology (CCSB) and Department of Cancer Biology, Dana-Farber Cancer Institute and the Department of Genetics, Harvard Medical School (Boston, MA), Marc Brehme is an employee and Marc Vidal is a Scientific Advisory Board member of Proteostasis Therapeutics, Inc. (Cambridge, MA).

Figures

Figure 1
Figure 1
Yeast protein–lipid-binding fingerprints as predictors of protein localization, domains and functions. (A) Yeast protein–lipid-binding map summarizing protein–lipid-binding frequencies, where lipids and proteins are grouped according to their metabolic pathways and LBDs, respectively. Box sizes are proportional to the number of proteins and lipids per group and the scale represents normalized number of interactions. (B) Complete linkage clustering of lipid-binding fingerprints reveals clades enriched in the annotations lipid metabolism (green), PH domain (pink), Bud-neck localization (violet) and punctate localization (turquoise). Adapted from Gallego et al (2010).
See this image and copyright information in PMC

Comment on

  • A systematic screen for protein-lipid interactions in Saccharomyces cerevisiae.
    Gallego O, Betts MJ, Gvozdenovic-Jeremic J, Maeda K, Matetzki C, Aguilar-Gurrieri C, Beltran-Alvarez P, Bonn S, Fernández-Tornero C, Jensen LJ, Kuhn M, Trott J, Rybin V, Müller CW, Bork P, Kaksonen M, Russell RB, Gavin AC. Gallego O, et al. Mol Syst Biol. 2010 Nov 30;6:430. doi: 10.1038/msb.2010.87. Mol Syst Biol. 2010. PMID: 21119626 Free PMC article.

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