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Editorial
. 2010 May 10:5:10.
doi: 10.4314/pamj.v5i1.56184.

When one can infect two: a reflection on the impact of HIV discordance on child HIV infection

Affiliations
Editorial

When one can infect two: a reflection on the impact of HIV discordance on child HIV infection

Agnes Binagwaho et al. Pan Afr Med J. .

Abstract

This is an opinion piece based on data and experience from Rwanda. The authors believe this opinion piece may help improve current programs on prevention of HIV transmission from mother to child in Africa taking into account the prevalence of HIV sero-discordance in couples. The authors recommend that if we want to ensure newborns stay HIV negative, PMTCT protocols should offer a series of HIV tests linked with antenatal visits and the lactation period as well as HIV testing of current sexual partners. Moreover, if the male partner is found to be positive and the woman is negative, programs should provide intensive counseling on the use of condoms. The lives of three individuals have the potential to be changed from HIV testing and counseling. Morally, this cannot be ignored.

Keywords: HIV; HIV discordance; PMTCT; Rwanda; Sero-discordant couples; children.

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References

    1. Dunkle K, Stephenson R, Karita E, Ewyn C, Kayitenkore K, Vwalika C. et al. New heterosexually transmitted HIV infections in married or cohabiting couples in urban Zambia and Rwanda: an analysis of survey and clinical data. Lancet. 2008;371:2183–2191. - PubMed
    1. Sephenson R, Barker J, Cramer R, Hall MA, Karita E, Choma E. et al. The demographic profile of serodiscordant couples enrolled in clinical research in Rwanda and Zambia. AIDS Care. 2008;20(3):395–405. - PubMed
    1. Lingappa JR, Lambdin B, Bukusi EA, Ngure K, Kavuma L, Inambao M. et al. Regional Differences in Prevalence of HIV-1 Discordance in Africa and Enrollment of HIV-1 Discordant Couples into an HIV-1 Prevention Trial. PLoS ONE. 2008;3(1):1411. - PMC - PubMed
    1. Desgrées-du-Loû A, Orne-Gliemann J. Couple-centred testing and counselling for HIV serodiscordant heterosexual couples in sub-Saharan Africa. Reprod Health Matters. 2008 Nov;16(32):151–61. - PubMed
    1. Republic of Rwanda. United Nations General Assembly Special Session on HIV and AIDS. Country Progress Report; Jan, 2008. Dec, 2009.

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