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. 2010 Aug;14(2):130-2.
doi: 10.5213/inj.2010.14.2.130. Epub 2010 Aug 31.

A Case of Bladder Cancer Found during a Workup for Urge Incontinence

Yun-Seob Song  1 , Kyu-Hyung Cho, Keun-Woo Kim, Jong-Hyun Yoon, Seung-Hwan Doo, Won-Jae Yang, Joo-Young Cho, Dong-Wha Lee
Affiliations

A Case of Bladder Cancer Found during a Workup for Urge Incontinence

Yun-Seob Song et al. Int Neurourol J. 2010 Aug.

Abstract

Irritative urinary symptoms may suggest the possibility of bladder cancer. We report a case of metastatic bladder cancer that was discovered during a workup for urge incontinence in a 65-year-old woman with a history of stomach cancer. She had a medical history of gastrectomy due to stomach cancer 4 years previously. The patient complained of urgency unresponsive to anticholinergic therapy. Cystoscopy revealed the presence of suspicious bladder mucosal lesions that were biopsied. The pathology was consistent with metastatic signet-ring cell adenocarcinoma. This case suggests that irritative urinary symptoms can be the first clinical manifestation in patients with bladder cancer.

Keywords: Bladder cancer; Stomach cancer; Urge incontinence.

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Figures

Figure 1
Figure 1
Pelvic computerized tomography showing thickened anterior bladder wall, suggesting tumoral infiltration.
Figure 2
Figure 2
Cystoscopy that revealed a suspicious bladder mucosal lesion in the anterior bladder wall.
Figure 3
Figure 3
Photomicrography showing infiltration of signet-ring cell adenocarcinoma in anterior bladder wall. A: Beneath the urothelium with chronic inflammation, discohesive cellular infiltration is noted. (H&E, ×200), B: Tumor cells disclose abundant vacuolated cytoplasm and eccentric nuclei. (H&E, ×400), C: PAS and d-PAS stain reveal positive finding in the tumor cells.(d-PAS, ×400), D: In previously operated stomach, tumor cells between the gastric glands show features of tumor cells of urinary bladder, suggestive of metastasis from the stomach. (H&E, ×400)
See this image and copyright information in PMC

References

    1. Valero Puerta JA, Medina Perez M, Garcia Carriazo M, Valpuesta Fernandez I, Sanchez Gonzalez M, Mompean FO. Bladder metastasis of signet-ring cell adenocarcinoma from the stomach. Arch Esp Urol. 2000;53:839–841. - PubMed
    1. Leddy FF, Peterson NE, Ning TC. Urogenital linitis plastica metastatic from stomach. Urology. 1992;39:464–467. - PubMed
    1. Messing ED. Urothelial tumors of the bladder. In: Wein AJ, Kavoussi LR, Novick AC, Partin AW, Peters CA, editors. Capbell-Walsh Urology. 8th ed. Philadelphia: Saunders; 2007. pp. 2407–2446.
    1. Saba NF, Hoening DM, Cohen SI. Metastatic signet-ring cell adenocarcinoma to the urinary bladder. Acta Oncol. 1997;36:219–220. - PubMed
    1. Nitti VW, Blaivas JG. Urinary incontinence: Epidemiology, pathophysiology, evaluation, and management overview. In: Wein AJ, Kavoussi LR, Novick AC, Partin AW, Peters CA, editors. Capbell-Walsh Urology. 8th ed. Philadelphia: Saunders; 2007. pp. 2046–2090.

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