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. 2010 Dec;17(4):333-9.
doi: 10.1007/s10880-010-9205-4.

Psychiatric symptoms and quality of life in patients affected by epidermolysis bullosa

Francesco Margari  1 , Paola A Lecce, Wanda Santamato, Patrizia Ventura, Nicola Sportelli, Giuseppina Annicchiarico, Ernesto Bonifazi
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Psychiatric symptoms and quality of life in patients affected by epidermolysis bullosa

Francesco Margari et al. J Clin Psychol Med Settings. 2010 Dec.

Abstract

The aim of our study was to provide a psychosocial and psychiatric evaluation of patients with epidermolysis bullosa (EB; a rare genetic disorder characterized by skin fragility), to assess psychological status, ascertain the presence of any psychiatric disorders and understand the impact of EB on quality of life. Twenty-five patients were assessed using a case record form and several standardized instruments. In 82% of patients, EB had a negative impact on quality of life and 80% of patients experienced psychiatric symptoms. Our findings revealed a high prevalence of psychosocial problems and psychiatric symptoms in patients with EB and suggested that a combined bio-psychosocial approach is the most appropriate therapeutic intervention.

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