[Hereditary thrombophilias--recommendations for genetic testing in the clinical praxis]

Abstract

Venous thromboembolism is a common serious clinical condition, in which genetic factors play an important role, too. The objective of this review is to summarize current knowledge regarding the hereditary thrombophilias and submit their simple classification. Recommended Consensus of the Czech Societies on Thrombosis and Haemostasis, Haematology and Medical Genetics for genetic testing in specific patients' groups at venous thromboembolism high-risk situation is also presented.