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Randomized Controlled Trial
. 2011 Jan;112(1):40-4.
doi: 10.1016/j.ijgo.2010.08.022. Epub 2010 Nov 30.

Oral misoprostol as an alternative to surgical management for incomplete abortion in Ghana

Joseph Taylor  1 , Ayisha Diop, Jennifer Blum, Obed Dolo, Beverly Winikoff
Affiliations
Randomized Controlled Trial

Oral misoprostol as an alternative to surgical management for incomplete abortion in Ghana

Joseph Taylor et al. Int J Gynaecol Obstet. 2011 Jan.

Abstract

Objective: To investigate whether 600-μg oral misoprostol is an effective alternative to manual vacuum aspiration (MVA) for the treatment of incomplete abortion.

Methods: From June 16, 2004, to July 20, 2005, 230 women of reproductive age presenting with incomplete abortion were randomized in an open-label trial to either 600-μg oral misoprostol or MVA for the treatment of incomplete abortion.

Results: Regardless of the assigned method, more than 98% of participants experienced complete uterine evacuation following initial treatment. Efficacy, acceptability, and satisfaction ratings were similar and high for both methods.

Conclusion: 600-μg oral misoprostol is a safe, effective, and acceptable alternative to MVA for the treatment of incomplete abortion.

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