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Comparative Study
. 1990 Apr;25(4):561-6.
doi: 10.1093/jac/25.4.561.

In-vitro synergy testing of nine antimicrobial combinations against Listeria monocytogenes

A P MacGowan  1 , H A Holt, D S Reeves
Affiliations
Comparative Study

In-vitro synergy testing of nine antimicrobial combinations against Listeria monocytogenes

A P MacGowan et al. J Antimicrob Chemother. 1990 Apr.

Abstract

In-vitro antimicrobial synergy against Listeria monocytogenes was assessed using nine combinations in chequerboard (bacteriostatic) tests and time-kill (bactericidal) studies. Ampicillin/gentamicin and trimethoprim/sulphamethoxazole were the most synergistic combinations in bacteristatic tests, whereas gentamicin with ampicillin, trimethoprim or vancomycin and trimethoprim/sulphamethoxazole were the most synergistic in bactericidal tests. Gentamicin-containing combinations were most effective at killing L. monocytogenes and those containing rifampicin least effective.

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