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. 1978 Aug;27(2):443-8.
doi: 10.1128/JVI.27.2.443-448.1978.

Proteolysis of noncapsid protein 2 of type 3 poliovirus at the restrictive temperature: breakdown of noncapsid protein 2 correlates with loss of RNA synthesis

S A Bowles, D R Tershak

Proteolysis of noncapsid protein 2 of type 3 poliovirus at the restrictive temperature: breakdown of noncapsid protein 2 correlates with loss of RNA synthesis

S A Bowles et al. J Virol. 1978 Aug.

Abstract

Inhibition of RNA synthesis of the LH strain of type 3 poliovirus at the restrictive temperature occurs concurrently with the breakdown of noncapsid virus-specific peptide 2. This finding, along with other reported data (B.D. Korant, In Proteases and Biological Control, p. 621-644, 1975), suggests that noncapsid virus-specific peptide 2 is a component of the viral replicase.

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References

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    1. Proc Natl Acad Sci U S A. 1974 Dec;71(12):4773-7 - PubMed
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