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Review
. 2010 Nov:36 Suppl 3:S8-14.
doi: 10.1016/S0924-8579(10)70004-2.

Emerging carbapenemases: a global perspective

Timothy R Walsh  1
Affiliations
Review

Emerging carbapenemases: a global perspective

Timothy R Walsh. Int J Antimicrob Agents. 2010 Nov.

Abstract

The celestial rise in antibiotic resistance among Gram-negative bacteria has challenged both the scientific and pharmaceutical sectors. The hallmark of this general increase is the unbridled dissemination of carbapenem resistance genes, namely KPC, OXA and metallo-β-lactamase variants. In particular, the media attention given to the NDM-1 metallo-β-lactamase has highlighted the global consequences of human behaviour on spreading antibiotic resistance.

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