Emerging carbapenemases: a global perspective
- PMID: 21129630
- DOI: 10.1016/S0924-8579(10)70004-2
Emerging carbapenemases: a global perspective
Abstract
The celestial rise in antibiotic resistance among Gram-negative bacteria has challenged both the scientific and pharmaceutical sectors. The hallmark of this general increase is the unbridled dissemination of carbapenem resistance genes, namely KPC, OXA and metallo-β-lactamase variants. In particular, the media attention given to the NDM-1 metallo-β-lactamase has highlighted the global consequences of human behaviour on spreading antibiotic resistance.
Copyright © 2010 Elsevier B.V. All rights reserved.
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