Development of long-acting nitrate delivery systems
- PMID: 2113000
- DOI: 10.1007/BF01417560
Development of long-acting nitrate delivery systems
Abstract
In this paper pharmaceutical and biopharmaceutical aspects on the development of long-acting nitrate delivery systems are reviewed. Basic considerations and requirements are also discussed. Recent product development activities are presented, with an emphasis on nitroglycerin in transdermal form and oral isosorbide-5-mononitrate controlled-release formulations.
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