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Review
. 1990:38 Suppl 1:S15-9.
doi: 10.1007/BF01417560.

Development of long-acting nitrate delivery systems

Affiliations
Review

Development of long-acting nitrate delivery systems

U E Jonsson. Eur J Clin Pharmacol. 1990.

Abstract

In this paper pharmaceutical and biopharmaceutical aspects on the development of long-acting nitrate delivery systems are reviewed. Basic considerations and requirements are also discussed. Recent product development activities are presented, with an emphasis on nitroglycerin in transdermal form and oral isosorbide-5-mononitrate controlled-release formulations.

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