Identification of the serum-responsive transcription initiation site of the zinc finger gene Krox-20
- PMID: 2113176
- PMCID: PMC360834
- DOI: 10.1128/mcb.10.7.3788-3791.1990
Identification of the serum-responsive transcription initiation site of the zinc finger gene Krox-20
Abstract
The Krox-20 gene is rapidly and transiently induced when quiescent 3T3 cells are stimulated to reenter the proliferative cycle. We identified the major serum-responsive transcription initiation site and found that it differs from the initiation sites previously identified for the Krox-20 gene. Transcripts from the major serum-responsive initiation site increased at least 40-fold in serum-stimulated cells compared with logarithmically growing cells.
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