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Review
. 2011 Feb;55(1):36-47.
doi: 10.1111/j.1600-0757.2010.00350.x.

Microbial shift and periodontitis

Alex B Berezow, Richard P Darveau
Review

Microbial shift and periodontitis

Alex B Berezow et al. Periodontol 2000. 2011 Feb.
No abstract available

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Figures

Fig. 1
Fig. 1
The process of biofilm formation. Initially, individual bacterial cells attach to a surface. These cells then produce a sticky extracellular polymeric substance, which aids in attachment and allows the biofilm to grow larger. As it matures, the biofilm takes on a distinctive architecture, including water channels and nutrient gradients. The diagram is courtesy of P. Dirckx at the MSU Center for Biofilm Engineering.
Fig. 2
Fig. 2
Examples of human diseases associated with a shift in the content of the microflora.
Fig. 3
Fig. 3
The various causes and treatments of periodontitis. Antibiotics, antiseptics, and probiotics have been used to control the microbial nature of periodontitis. Host modulation therapy has been used to reduce the destructive inflammatory response underlying periodontitis. Photodynamic therapy, a unique and promising technology, has been shown to address both the microbial and immunological basis of the disease. Proper diet and hygiene have been used to treat the environmental and behavioral aspects of periodontitis. As of yet, no treatment exists to address any potential underlying genetic predisposition to periodontitis.
See this image and copyright information in PMC

References

    1. Aas JA, Paster BJ, Stokes LN, Olsen I, Dewhirst FE. Defining the normal bacterial flora of the oral cavity. J Clin Microbiol. 2005;43:5721–5732. - PMC - PubMed
    1. Al-Ahmad A, Roth D, Wolkewitz M, Wiedmann-Al-Ahmad M, Follo M, Ratka-Kruger P, Deimling D, Hellwig E, Hannig C. Change in diet and oral hygiene over an 8-week period: effects on oral health and oral biofilm. Clin Oral Investig. 2009 - PubMed
    1. Al-Rasheed A, Scheerens H, Rennick DM, Fletcher HM, Tatakis DN. Accelerated alveolar bone loss in mice lacking interleukin-10. J Dent Res. 2003;82:632–635. - PubMed
    1. An D, Parsek MR. The promise and peril of transcriptional profiling in biofilm communities. Curr Opin Microbiol. 2007;10:292–296. - PubMed
    1. Avila M, Ojcius DM, Yilmaz O. The oral microbiota: living with a permanent guest. DNA Cell Biol. 2009;28:405–411. - PMC - PubMed

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