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Review
. 2010;64(5):303-8.
doi: 10.2533/chimia.2010.303.

Recent biomimetic and organocatalytic syntheses of alpha-tocopherol

Antoinette Chougnet  1 , Kegang Liu, Wolf D Woggon
Affiliations
Free article
Review

Recent biomimetic and organocatalytic syntheses of alpha-tocopherol

Antoinette Chougnet et al. Chimia (Aarau). 2010.
Free article

Abstract

We report here on our efforts to develop new strategies for the synthesis of alpha-tocopherol, the biologically most significant member of the vitamin E family. This review comprises five new methods to generate the chiral chromane of alpha-tocopherol with overall up to 29% yield from commercially available material and up to 94% de.

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