Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Review
. 2011 Winter;51(1):77-91.
doi: 10.1097/IIO.0b013e3182010f29.

Current update on retinoblastoma

Samuel K Houston, Timothy G Murray, Stacey Quintero Wolfe, Cristina E Fernandes
Review

Current update on retinoblastoma

Samuel K Houston et al. Int Ophthalmol Clin. 2011 Winter.
No abstract available

PubMed Disclaimer

Figures

Figure 1
Figure 1
Leukocoria in a child with retinoblastoma (left eye).
Figure 2
Figure 2
Larger macular retinoblastoma before treatment (left), and tumor after chemoreduction and laser consolidation (right).
Figure 3
Figure 3
Tumor control with sub-Tenon’s carboplatin combined with focal laser ablation. Multifocal, unilateral retinoblastoma (left); following sub-Tenon’s injection of carboplatin, drug is seen posterior to retina and tumor (middle); following laser and sub-Tenon’s carboplatin, tumor control is evident at 5 year follow-up (right).
Figure 4
Figure 4
Superselective ophthalmic artery cannulation resulting in local administration of chemotherapy.
Figure 5
Figure 5
Wide-angle photograph (top-left) of tumor activity in area of previous laser treatment. Intraoperative SD-OCT – 3-D image (top-right), fundus (bottom-left) and B-scan (bottom-right)
See this image and copyright information in PMC

References

    1. Wessels G, Hesseling PB. Outcome of children treated for cancer in the Republic of Namibia. Med Pediatr Oncol. 1996;27:160–164. - PubMed
    1. Bowman RJ, Mafwiri M, Luthert P, Luande J, Wood M. Outcome of retinoblastoma in east Africa. Pediatr Blood Cancer. 2008;50:160–162. - PubMed
    1. Knudson AG., Jr Mutation and cancer: statistical study of retinoblastoma. Proc Natl Acad Sci U S A. 1971;68:820–823. - PMC - PubMed
    1. Huang HJ, Yee JK, Shew JY, et al. Suppression of the neoplastic phenotype by replacement of the RB gene in human cancer cells. Science. 1988;242:1563–1566. - PubMed
    1. Khidr L, Chen PL. RB, the conductor that orchestrates life, death and differentiation. Oncogene. 2006;25:5210–5219. - PubMed

Publication types

MeSH terms