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Case Reports
. 2009 Jul 22;1(1):e24.
doi: 10.4081/rt.2009.e24.

Cystadenofibroma of the rete ovarii: a case report with review of literature

Manisha Ram  1 , Abdel Abdulla, Khalil Razvi, Ivilina Pandeva, Awatif Al-Nafussi
Affiliations
Case Reports

Cystadenofibroma of the rete ovarii: a case report with review of literature

Manisha Ram et al. Rare Tumors. .
No abstract available

Keywords: cystadenofibroma; immunohistochemistry.; ovary; rete ovarii; rete testis.

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Conflict of interest statement

Conflict of interest: the authors reported no potential conflict of interests.

Figures

Figure 1
Figure 1
Gross photograph showing bi-valved specimen depicting solid- cystic appearance.
Figure 2
Figure 2
Microphotograph showing diffuse replacement of ovary by epithelial and stromal proliferation (H&E × 40).
Figure 3
Figure 3
Microphotograph showing variably sized irregular slit-like spaces lined by monolayered bland cuboidal epithelium and intervening mature fibrotic stroma (H&E ×200).
Figure 4
Figure 4
Microphotograph showing a markedly dilated cyst with papillae projecting into the cyst lumen (H&E ×200).
Figure 5
Figure 5
Microphotograph showing high power view of bland cuboidal lining of papillae (H&E ×400).
Figure 6
Figure 6
Microphotograph showing bland cuboidal lining of tubules with occasional ciliated cells (H&E ×600).
Figure 7
Figure 7
Microphotograph showing cellular fibrotic stroma, reminiscent of rete ovarii (H&E ×200).
Figure 8
Figure 8
Microphotograph showing focal smooth muscle fibers (highlighted by SMA immunostaining) in the stroma (H&E ×200).
Figure 9
Figure 9
Microphotograph showing intense and diffuse ER positivity in epithelial cells (H & DAB × 200).
Figure 10
Figure 10
Microphotograph showing intense and diffuse CK7 positivity in epithelial cells (H & DAB ×200).
Figure 11
Figure 11
Microphotograph showing no staining in epithelial cells for thrombomodulin (right), whereas the normal ovarian surface epithelial lining (left) is positive for it, acting as an internal control (H & E ×200).
Figure 12
Figure 12
Microphotograph showing lack of a distinct basement membrane, highlighted by negative staining for laminin (H & DAB ×400).
See this image and copyright information in PMC

References

    1. Rutgers JL, Scully RE. Cysts (cystadenomas) and tumours of rete ovarii. Int J Gynec Pathol. 1988;7:330–42. - PubMed
    1. Long GG. Apparent mesonephric duct (rete anlage) origin for cysts and proliferative epithelial lesions in the mouse ovary. Toxic Pathol. 2002;3:592–8. - PubMed
    1. Heatley MK. Adenomatous hyperplasia of the rete ovarii. Histopathol. 2000;36:383–4. - PubMed
    1. Jones EC, Murray SK, Young RH. Cysts and epithelial proliferations of the testicular collecting system (including rete testis) Semin Diagn Pathol. 2000;17:270–93. - PubMed
    1. Devouassoux-Shisheboran M, Silver SA, Tavassoli FA. Wolffian Adnexal Tumor, so called female adnexal tumour of probable Wolffian origin (FATWO): immunohistochemical evidence in support of a Wolffian origin. Hum Pathol. 1999;30:856–63. - PubMed

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