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Case Reports
. 2010 Mar 31;2(1):e17.
doi: 10.4081/rt.2010.e17.

Rapid progression of littoral cell angioma of the spleen in a man with multiple infections

Errol Berman  1 , Francis Ikpatt, Di Wang, Alan Dembner, N Peter Zauber
Affiliations
Case Reports

Rapid progression of littoral cell angioma of the spleen in a man with multiple infections

Errol Berman et al. Rare Tumors. .

Abstract

Littoral cell angioma is an uncommon primary vascular neoplasm of the spleen. It frequently follows a benign course, but cases with aggressive behavior have been described. We present a case of this rare disease highlighting radiological examinations showing a rapid increase in the size of the spleen as well as an increase in the number and size of existing nodules. We also discuss the relationship of this disorder to chronic infections and its possible association with Epstein Barr virus.

Keywords: infections; littoral cell angioma; spleen.

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Conflict of interest statement

Conflict of interest: the authors report no conflicts of interest.

Figures

Figure 1
Figure 1
(A) Initial computerized tomography (CT) scan of the abdomen showing a slightly enlarged spleen with several poorly defined masses. (B) Second CT scan of the abdomen showing a markedly enlarged spleen with increased numbers and size of intra-splenic nodules.
Figure 2
Figure 2
Hematoxylin and eosin stain of the cut surface of the spleen; magnification, 200×. Insert: higher magnification of a sinusoid with the arrow indicating a littoral cell; magnification, 400×.
See this image and copyright information in PMC

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