Aggressive angiomyxoma in the inguinal region: a case report

Abstract

Introduction: Aggressive angiomyxoma is a rare myxoid mesenchymal tumor of the pelvis and perineum, which occurs almost exclusively in adult women. The tumor is especially rare in men.

Case presentation: We report the case of a 68-year-old Japanese man with a slowly growing inguinal swelling. At surgery, a huge mass in the soft tissue of the inguinal region was found, not involving the adjacent organs. The morphologic picture was compatible with aggressive angiomyxoma of the inguinal region.

Conclusions: Aggressive angiomyxoma is a very rare, locally infiltrative neoplasm. Thus, after surgery, close follow-up is needed because of a high risk of local recurrence.

Figure 1

A slowly growing swelling of the soft tissue in the inguinal region. (a) Swelling of the soft tissue in the right inguinal region was observed. (b) Magnetic resonance imaging revealed that the lesion (arrows) was isointense relative to muscle on the T₁-weighted image.

Figure 2

Macroscopic and microscopic findings of the lesion. (a) Macroscopic finding of the tumor. The tumor measured 7.5 cm and had a relatively clear margin. The cut surface of the tumor was smooth, homogeneous, and gray-white without necrosis or hemorrhage. (b) Microscopic findings of the lesion (hematoxylin and eosin stain, ×200). The tumor was composed of spindle cells and blood vessels with myxoid stroma.