Pushing the envelope to reduce sedation in critically ill patients

Affiliations

¹ University of Pittsburgh Medical Center, Department of Critical Care Medicine, 606 D Scaife Hall, 3550 Terrace Street, University of Pittsburgh, Pittsburgh, PA 15261, USA.

Comment

Olufunmilayo Ogundele et al. Crit Care. 2010.

. 2010;14(6):339.

doi: 10.1186/cc9339. Epub 2010 Dec 9.

¹ University of Pittsburgh Medical Center, Department of Critical Care Medicine, 606 D Scaife Hall, 3550 Terrace Street, University of Pittsburgh, Pittsburgh, PA 15261, USA.

No abstract available

Comment on

A protocol of no sedation for critically ill patients receiving mechanical ventilation: a randomised trial.
Strøm T, Martinussen T, Toft P. Strøm T, et al. Lancet. 2010 Feb 6;375(9713):475-80. doi: 10.1016/S0140-6736(09)62072-9. Epub 2010 Jan 29. Lancet. 2010. PMID: 20116842 Clinical Trial.

1. Strom T, Martinussen T, Toft P. A protocol of no sedation for critically ill patients receiving mechanical ventilation: a randomized trial. Lancet. 2010;375:475–480. doi: 10.1016/S0140-6736(09)62072-9. - DOI - PubMed
1. Brush DR, Kress JP. Sedation and analgesia for the mechanically ventilated patient. Clin Chest Med. 2009;30:131–141. doi: 10.1016/j.ccm.2008.09.001. - DOI - PubMed
1. Kollef MH, Levy NT, Ahrens TS, Schaiff R, Prentice D, Sherman G. The use of continuous i.v. sedation is associated with prolongation of mechanical ventilation. Chest. 1998;114:541–548. doi: 10.1378/chest.114.2.541. - DOI - PubMed
1. Kress JP, Pohlman AS, O'Connor MF, Hall JB. Daily interruption of sedative infusions in critically ill patients undergoing mechanical ventilation. N Engl J Med. 2000;342:1471–1477. doi: 10.1056/NEJM200005183422002. - DOI - PubMed
1. Sessler CN, Pedram S. Protocolized target-based sedation and analgesia in the ICU. Crit Care Clin. 2009;25:489–513. doi: 10.1016/j.ccc.2009.03.001. - DOI - PubMed