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Comment
. 2010;14(6):338.
doi: 10.1186/cc9338. Epub 2010 Dec 9.

Etomidate and adrenal insufficiency: the controversy continues

Affiliations
Comment

Etomidate and adrenal insufficiency: the controversy continues

Alyssa Majesko et al. Crit Care. 2010.
No abstract available

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References

    1. de Jong FH, Mallios C, Jansen C, Scheck PA, Lamberts SW. Etomidate suppresses adrenocortical function by inhibition of 11 beta-hydroxylation. J Clin Endocrinol Metab. 1984;59:1143–1147. doi: 10.1210/jcem-59-6-1143. - DOI - PubMed
    1. Malerba G, Romano-Girard F, Cravoisy A. et al.Risk factors of relative adrenocortical deficiency in intensive care patients needing mechanical ventilation. Intensive Care Med. 2005;31:388–392. doi: 10.1007/s00134-004-2550-8. - DOI - PubMed
    1. Ledingham IM, Watt I. Influence of sedation on mortality in critically ill multiple trauma patients [abstract] Lancet. 1983;321:1270. doi: 10.1016/S0140-6736(83)92712-5. - DOI - PubMed
    1. Annane D, Sebille V, Troche G, Raphael JC, Gajdos P, Bellissant E. A 3-level prognostic classification in septic shock based on cortisol levels and cortisol response to corticotropin. JAMA. 2000;283:1038–1045. doi: 10.1001/jama.283.8.1038. - DOI - PubMed
    1. de Jong MF, Beishuizen A, Spijkstra JJ, Groeneveld AB. Relative adrenal insufficiency as a predictor of disease severity, mortality, and beneficial effects of corticosteroid treatment in septic shock. Crit Care Med. 2007;35:1896–1903. doi: 10.1097/01.CCM.0000275387.51629.ED. - DOI - PubMed

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