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Comment
. 2010 Dec 9;68(5):809-11.
doi: 10.1016/j.neuron.2010.11.037.

Cholinergic signaling through synaptic SK channels: it's a protein kinase but which one?

James Maylie  1 , John P Adelman
Affiliations
Comment

Cholinergic signaling through synaptic SK channels: it's a protein kinase but which one?

James Maylie et al. Neuron. .

Abstract

Cholinergic signaling modulates synaptic responses and influences cognition. In this issue of Neuron, two groups (Buchanan et al. and Giessel and Sabatini) present evidence that cholinergic signaling enhances postsynaptic responses in CA1 neurons by decreasing synaptic SK channel activity. However, they come to different conclusions about the protein kinases involved in this process.

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References

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