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Comment
. 2010 Dec 16;8(6):464-6.
doi: 10.1016/j.chom.2010.11.010.

Keeping viruses in Chk: DNA damage signaling puts the brakes on transformation

Caroline E Lilley  1 , Matthew D Weitzman
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Keeping viruses in Chk: DNA damage signaling puts the brakes on transformation

Caroline E Lilley et al. Cell Host Microbe. .
Free article

Abstract

Oncogenic viruses infect many cells but rarely lead to tumorigenesis. In this issue of Cell Host & Microbe, Nikitin et al. describe how a protective DNA damage response acts to suppress transformation in the majority of cells latently infected with Epstein-Barr virus (EBV).

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