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. 1978 Aug;75(8):4047-51.
doi: 10.1073/pnas.75.8.4047.

A Drosophila mutant with a temperature-sensitive block in nerve conduction

C F Wu, B Ganetzky, L Y Jan, Y N Jan, S Benzer

A Drosophila mutant with a temperature-sensitive block in nerve conduction

C F Wu et al. Proc Natl Acad Sci U S A. 1978 Aug.

Abstract

A mutant, napts (no action potential, temperature-sensitive), is described in which axonal conduction fails at high temperature. Synaptic transmission at the larval neuromuscular junction is unimpaired. Larvae and adults are rapidly paralyzed at restrictive temperatures; they recover rapidly when the temperature is decreased. The mutant gene is recessive and is located on the second chromosome at map position 56.

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