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. 2009 Sep 9:2:17-22.
doi: 10.4137/cpath.s3091.

Adenomatoid tumor of testis

Affiliations

Adenomatoid tumor of testis

Waqas Amin et al. Clin Med Pathol. .

Abstract

Adenomatoid tumors are responsible for 30% of all paratesticular masses. These are usually asymptomatic, slow growing masses. They are benign tumors comprising of cords and tubules of cuboidal to columnar cells with vacuolated cytoplasm and fibrous stroma. They are considered to be of mesothelial origin supported by histochemical studies and genetic analysis of Wilms tumor 1 gene expression. Excision biopsy is both diagnostic and therapeutic procedure. The main clinical consideration is accurate diagnosis preventing unnecessary orchiectomy. Diagnostic studies include serum tumor markers (negative alpha fetoprotein, beta HCG, LDH) ultrasonography (hypoechoic and homogenous appearance) and frozen section.

Keywords: adenomatoid tumor; paratesticluar masses.

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Figures

Figure 1.
Figure 1.
A low power view of a paratesticular adenomatoid tumor. Note the dilated tubules giving the appearance of endothelial spaces, adjacent to the normal uninvolved testicular parenchyma (4x, H & E).
Figure 2.
Figure 2.
Higher power view showing the tubular pattern of growth with dilated spaces and intervening fibrous stroma with a smooth muscle component (20x H & E).
Figure 3.
Figure 3.
A higher power view of the neoplasm with predominant component consisting of tubules with intervening single cells with a vacuolated appearance, a characteristic finding in adenomatoid tumors (40x, H & E).

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