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Case Reports
. 2010 Aug 2:2010:352476.
doi: 10.4061/2010/352476.

A case of papillary thyroid carcinoma in struma ovarii and review of the literature

Affiliations
Case Reports

A case of papillary thyroid carcinoma in struma ovarii and review of the literature

W D Salman et al. Patholog Res Int. .

Abstract

Malignancy in struma ovarii is a rare form of ovarian germ cell tumour. Because of its rarity, the diagnosis and management of the tumour have not been clearly defined. We present a case of 67- year-old female with papillary carcinoma arising in struma ovarii and review the literature on malignancy in struma ovarii cases, focusing on management of these cases.

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Figures

Figure 1
Figure 1
Low-magnification view of benign thyroid tissue in the ovary.
Figure 2
Figure 2
Areas with benign follicles as well as malignant papillary architecture.
Figure 3
Figure 3
Papillary architecture with fibrovascular core.
Figure 4
Figure 4
Areas with optically clear nuclei, thickened nuclear membrane, and overlapping nuclei representing papillary carcinoma.
Figure 5
Figure 5
Areas with papillary structures and psamomma bodies.

References

    1. Devaney K, Snyder R, Norris HJ, Tavassoli FA. Proliferative and histologically malignant struma ovarii: a clinicopathologic study of 54 cases. International Journal of Gynecological Pathology. 1993;12(4):333–343. - PubMed
    1. Kostoglou-Athanassiou I, Lekka-Katsouli I, Gogou L, Papagrigoriou L, Chatonides I, Kaldrymides P. Malignant struma ovarii: report of a case and review of the literature. Hormone Research. 2002;58(1):34–38. - PubMed
    1. Roth LM, Talerman A. The enigma of struma ovarii. Pathology. 2007;39(1):139–146. - PubMed
    1. Makani S, Kim W, Gaba AR. Struma Ovarii with a focus of papillary thyroid cancer: a case report and review of the literature. Gynecologic Oncology. 2004;94(3):835–839. - PubMed
    1. Roth LM, Karseladze AI. Highly differentiated follicular carcinoma arising from struma ovarii: a report of 3 cases, a review of the literature, and a reassessment of so-called peritoneal strumosis. International Journal of Gynecological Pathology. 2008;27(2):213–222. - PubMed

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