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. 2011 Feb 28;47(8):2294-6.
doi: 10.1039/c0cc03711g. Epub 2010 Dec 9.

Silver nanocluster aptamers: in situ generation of intrinsically fluorescent recognition ligands for protein detection

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Silver nanocluster aptamers: in situ generation of intrinsically fluorescent recognition ligands for protein detection

Jaswinder Sharma et al. Chem Commun (Camb). .

Abstract

We have synthesized an intrinsically fluorescent recognition ligand that combines the high fluorescence quantum yield (>50%) of oligonucleotide templated AgNCs with the specificity and strong binding affinity of DNA aptamers for their target proteins, to develop a new strategy for detection of specific proteins.

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