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Review
. 2011 Jan;79(1):21-5.
doi: 10.1055/s-0029-1245885. Epub 2010 Dec 9.

[Variety of symptoms after drug use of gamma-hydroxybutyric acid (GHB)]

[Article in German]
N Galldiks  1 , I Kadow, A Bechdolf, G R Fink, J Klosterkötter, J Kuhn
Affiliations
Review

[Variety of symptoms after drug use of gamma-hydroxybutyric acid (GHB)]

[Article in German]
N Galldiks et al. Fortschr Neurol Psychiatr. 2011 Jan.

Abstract

Gamma-hydroxybutyric acid (GHB, "liquid ecstasy") and its legal prodrugs gamma-butyrolactone and 1,4-butanediol are gaining importance as recreational drugs in Germany. Because of the wide availability of GHB and its prodrugs physicians are increasingly being confronted with cases of intoxication. The effect of GHB intoxication is comparable with those of alcohol and/or benzodiazepines. Likewise, symptoms of withdrawal may occur. In this review, we summarise current data regarding the history, pharmacodynamics and pharmacokinetics of the drug as well as the relevant symptoms of intoxication or withdrawal as they pertain to neurology and psychiatry.

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